The Effect of Systemic Proteolytic Enzymes on Postoperative Inflammatory Response and Quality of Life after Surgical Extraction of Impacted Mandibular Third Molar

Dunya Abdulmunem Albayati; Salwan Yousif Bede

doi:10.54133/ajms.v7i1.848

المؤلفون

Dunya Abdulmunem Albayati Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Baghdad, Baghdad, Iraq
Salwan Yousif Bede Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Baghdad, Baghdad, Iraq https://orcid.org/0000-0002-0693-933X

DOI:

https://doi.org/10.54133/ajms.v7i1.848

الكلمات المفتاحية:

Bromelain، Health care، Pain، Quality of life، Third molar، Tibrolin

الملخص

Background: The surgical extraction of impacted third molar usually results in postoperative inflammation manifested as pain, facial swelling and trismus which may cause deterioration in the patient’s quality of life. Methods: This randomized controlled study included 56 patients indicated for surgical extraction of IMTM under local anesthesia. These patients were randomly assigned into two groups: a study group that included patients who received Tibrolin® postoperatively and a control group that did not. The predictor variable was whether to use SET or not. Pain measured by the pain numerical rating scale (NRS), facial swelling, and the degree of trismus were the outcome variables. The Arabic version of the Oral Health Impact Profile 5 (OHIP5-Ar) questionnaire was used to measure quality of life (QoL) on the day of surgery (day 1) and on days 3, 7, and 13. Results: The study group demonstrated significantly lower pain scores postoperatively on day 1 and a lesser degree of facial swelling on day 3 compared to the control group, while no significant differences were observed regarding the other time intervals. There were no significant differences in the degree of trismus or QoL between the two groups. Conclusions: Tibrolin® administration following the surgical extraction of IMTM might reduce post-operative complaints in patients with surgical extraction of IMTM.

التنزيلات

بيانات التنزيل غير متوفرة بعد.

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