Solvent Role in Organic Chemistry in Comparison with Organic Synthesis under Solvent-Free Condition (Green Chemistry): A Mini Literature Review

المؤلفون

  • Sahar Balkat Aljuboori Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Rafidain University College, Baghdad 10052, Iraq https://orcid.org/0000-0002-6299-5723
  • Nedaa Abdulhameed Abdulrahim Department of Pharmaceutical Chemistry, College of Pharmacy, University of Baghdad, Baghdad, Iraqr https://orcid.org/0000-0002-7397-5584
  • Shuhad Yassen Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Rafidain University College, Baghdad 10052, Iraq https://orcid.org/0000-0003-1261-3309
  • Heba Hashim Khaleel Department of Pharmaceutical Chemistry, College of Pharmacy, University of Baghdad, Baghdad, Iraq

DOI:

https://doi.org/10.54133/ajms.v3i.94

الكلمات المفتاحية:

Organic synthesis، Green chemistry، Purification، Solvent-free reaction

الملخص

Solvents are important components in the pharmaceutical and chemical industries, and they are increasingly being used in catalytic reactions. It is having a significant influence on the kinetics and thermodynamics of reactions, and it can significantly change product selectivity. Solvents can influence product selectivity, conversion rates, and reaction rates. However, solvents have received a lot of attention in the field of green chemistry. This is due to the large amount of solvent that is frequently used in a process or formulation, particularly during the purification steps. However, neither the solvent nor the active ingredient in a formulation is directly responsible for the reaction product's composition. Because these characteristics have little bearing on how well or quickly the system in which the solvent is applied works, it appears unnecessary to use toxic, combustible, or environmentally hazardous solvents. However, the beneficial properties of the solvent required for the application are strongly linked to these unfortunate side effects of solvent use. Distillation can be used to recover and purify solvents because they are volatile. However, this process can produce unwanted air pollutants and be hazardous to workers during exposure.

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التنزيلات

بيانات التنزيل غير متوفرة بعد.

التنزيلات

منشور

2022-12-17

كيفية الاقتباس

Aljuboori, S. B., Abdulrahim, N. A., Yassen, S., & Khaleel, H. H. (2022). Solvent Role in Organic Chemistry in Comparison with Organic Synthesis under Solvent-Free Condition (Green Chemistry): A Mini Literature Review. Al-Rafidain Journal of Medical Sciences, 3, 109–115. https://doi.org/10.54133/ajms.v3i.94

إصدار

القسم

Review article

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