Evaluate the Efficiency of Sage (Salvia Officinalis) and Curcumin Mouthwash in the Treatment of Recurrent Aphthous Stomatitis ( Comparative Study)

Abstract

Recurrent Aphthous Stomatitis (RAS) is a common oral disorder that the clear etiology is un known. These ulcers are painful and caused serious complications in eating, talking and swallowing that make an individual requires treatment to relieve these symptoms. Corticosteroids and analgesics considered the first choice for RAS patients. Some of these drugs lead to many complications; so many therapies have been tried to find alternative modalities. Natural herbs and plants gain global interest due to their distinct properties, recently they are directed to be employed in medicine and dental care. Sage (Salvia officinalis) and curcumin are among the most prominent herbal substances that have been used in medicine and dentistry. The present study was carried out to evaluate the efficacy of a mouthwash containing Sage (Salvia officinalis) with curcumin extracts as natural herbal medicine in treating recurrent aphthous stomatitis (RAS). Method: The study was carried for the period of (November 2019-January 2020), where 74 patients visited a consultant educational clinic of Al-Mustansiriyah University, Collage of Dentistry complaining of minor oral ulcers. A special questionnaire was designed for the purpose of data collection. Criteria in this study include the evaluation of ulcer size, remission of pain, and time needed for complete healing. Two study groups were included, the first group uses Sage mouthwash and second group curcumin mouth wash, both groups rinse for 1 minute five times for five days, the comparisons were based on the results of statistical analysis conducted by SPSS.Results: Through statistical comparison between the two studied groups, the pain mean of apthous ulcer in the second visit was 3.93±1.52 sage group that is less than the pain mean in the curcumin group 4.73±1.2, and it was significant as for the third visit. Decrease in the pain mean of the sage group compared with the curcumin group 0.81±1.09 and 2.77±1.59 respectively, highly significant difference between the two groups (( t=-6.257,P=0.000). The mean of healing duration was5.32± 1.65 in the sage group, while in the curcumin group was 4.56 ± 1.20, there was a significant difference between the two studied groups. (t=-2.010,P = 0.048) .Conclusion: Herbal medicine can be acknowledged as a promising therapy. There is some confirmation of the potential utilization of the natural herbal medicines according to improved RAS outcome measures. Recommendation: More studies should be conducted with promising natural herbs which deals with more benefits and achievements in the dental field.